Reticulated platelets predict cardiovascular death in acute coronary syndrome patients
نویسندگان
چکیده
Francesca Cesari1; Rossella Marcucci1; Anna Maria Gori2; Roberto Caporale3; Alessandra Fanelli3; Giulia Casola1; Daniela Balzi4; Alessandro Barchielli4; Serafina Valente1; Cristina Giglioli1; Gian Franco Gensini2; Rosanna Abbate1 1Department of Clinical and Experimental Medicine, Thrombosis Centre, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy; 2Don Carlo Gnocchi Foundation Italy, Florence, Italy; 3Central Laboratory, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy; 4Epidemiology Unit, Local Health Unit 10, Florence, Italy
منابع مشابه
Reticulated platelets predict cardiovascular death in acute coronary syndrome patients. Insights from the AMI-Florence 2 Study.
Reticulated platelets (RP) are newly-formed platelets with a greater mass, a residual amount of RNA and an increased prothrombotic potential. No studies investigating the association between RP and the risk of cardiovascular death in acute coronary syndrome (ACS) patients are available. In the frame of the AMI-Florence 2 study, we investigated RP in 229 (154 M/ 75 F) ACS patients (125 ST-elevat...
متن کاملImmature platelet fraction: a new prognostic marker in acute coronary syndrome.
The role of platelets in the pathogenesis of acute coronary syndrome (ACS) is well recognized. Persistent platelet activation despite antithrombotic therapy has an influence on the severity of ischemic cardiomyopathy. Reticulated platelets are the youngest form of circulating platelets. They are larger than senescent platelets, contain residual RNA that confers a reticulated appearance, and are...
متن کاملReticulated platelets: analytical aspects and clinical utility.
Reticulated platelets are immature platelets circulating in blood; they reflect the activity of megakaryopoiesis in the bone marrow. Therefore, they can be used as a non-invasive test in patients with thrombocytopenia in various clinical conditions. The preferred method of analysis is by flow cytometry. However, there is an evident lack of analytical standardization, making it difficult to comp...
متن کاملDynamic changes in purine catabolism in patients with acute coronary syndrome that underwent percutaneous coronary intervention
Background: Cardiovascular diseases are global problems. They are causes of death in about 43% of people worldwide and may become the most widespread reason of death by 2020. The prognosis is directly dependent to immediate diagnosis and on time treatment. Introduction of new biochemical markers as the early diagnosis of complications after coronary revascularization is very important in this p...
متن کاملEffect of Cardiac Rehabilitation Program Based on Combined Training on VEGF/Endostatin Gene Expression Ratio in Patients with Acute Coronary Syndrome
Background: Coronary artery disease is one of the most common causes of death in the world. With the increase in the incidence of these diseases, surgical and non-surgical interventions followed by cardiovascular rehabilitation programs have become more important. The process of angiogenesis and improvement of blood flow is considered as one of the therapeutic goals in these patients, and vascu...
متن کامل